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Pearls of Knowledge: Sick Sinus Syndrome

Wednesday, December 03, 2025

Primary Blog/Pearls of Knowledge: Sick Sinus Syndrome

Rhythm Interpretation: Sick Sinus Syndrome

Pearls of Knowledge © BrainyNurses.com

Sick sinus syndrome is abnormal function of the SA node due of a wide range of abnormalities. Shifting of the pacing site within the SA node accounts for the changes in heart rate and P wave configurations which will be seen. In atrial fibrillation, damage to the AV node can also result in sick sinus syndrome. 

Sick sinus syndrome is often known as “tachy-brady” syndrome. The slower the rate, the more symptomatic the patient will be. Atropine may be used if it is symptomatic bradycardia. Generally, a pacemaker will be inserted. Anticoagulation should be considered if a very marked tachy-brady syndrome as clots may form during the bradycardic episodes and be released with the tachycardic ones.

Rhythm Analysis

(Continuous rhythm strips)

• Begins as a sinus tachycardia, rate of 125 BPM.
• Slows to around 80 BPM on the second strip.
• The heart rate is the slowest on the fourth strip with a heart rate of 20 BPM.
• Note the ST segment depression and symmetrical T wave inversion indicative of ischemia with the slower rates.

Rhythm Analysis

(Continuous rhythm strips)

• Underlying rhythm is atrial fibrillation.
• Begins with a heart rate of 42-50 BPM in the initial strip.
• Increases to 125-150 BPM on the second strip and then slows at the end of the third strip.
• The changes in heart rate are due to AV nodal disease.
• Typically, atrial fibrillation will have a more consistent ventricular rate.​

Summary

Sick sinus syndrome is more common with damage to the SA node but the AV node is also susceptible and in atrial fibrillation, that damage can present as a “tachy-brady” rhythm. Due to the damage to the conduction system, a permanent pacemaker will be considered.

To enhance care provided for cardiac patients, check out Comprehensive Rhythm Review and Clinical Application. It is on-line, on-demand, with voice-over-power-point. The extensive handout is easy to follow and includes our “In My Pocket” cards as a ready reference tool.

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